BM-011 molecule of the month
Compound BM-011 (also known as EG-011) has been selected as molecule of the month November 2022 by Drug Hunter.
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Drug Hunter identified the compound as a novel approach to target WASp for hematological cancers. The serendipitous discovery of the WASp activator without kinase activity from a scaffold hop of a BTKi showed promising in vitro data recapitulated during in vivo experiments.
The full report can be found here: Drug Hunter molecule of the month